Star Trek: The Original Series was excellent for taking on fringe questions like race, greek gods and in the case of Episode "Operation Annhilate", posessions. The episode explores the parasitic mechanism, effect on hosts (physical & psychological-behavorial), complexity of curing and means of working around it. Must watch!
Star Trek: The Original Series / Operation Annihilate
I will let you watch the episode and conclude how close the writers come to the "cure" for posessions in this story. Its fun to watch how Spock shows his failing resistence to the parasite posession with twitches. Credits to writer